​

​

Years Ended December 31, 

​

​

2024

2023

Operating Expenses:

​

​

​

​

​

​

PMN310 development program costs

​

$

8,275,268

​

$

4,776,411

Other non-employee research and development costs

​

772,501

​

1,602,164

Employee costs

​

​

3,336,580

​

​

3,102,238

Other general and administrative costs

​

​

4,443,129

​

​

4,781,920

Net Operating Loss:

​

$

16,827,478

​

$

14,262,733

Other segment items^(a)

​

​

(19,606,351)

​

​

(1,050,251)

Net (Income) Loss:

​

$

(2,778,873)

​

$

13,212,482

​

​

​

​

​

​

​

Reconciliation of profit or loss

​

​

​

​

​

​

Adjustments and reconciling items

​

​

—

​

​

—

Consolidated net (income) loss:

​

$

(2,778,873)

​

$

13,212,482

​

​

​

​

​

​

​

^(a)Other segment items included in segment (income) loss include changes in warrant liability, interest income, and interest expense, and in 2024 Loss on issuance of common shares, warrants, and pre-funded warrants in July 2024 PIPE